Why Does Most Skincare Sit on the Surface? It's A Skin Barrier Problem

Did you know that up to 90% of skincare products never fully absorb?

The skin’s top job is protection. Its outer barrier is naturally hydrophobic (water-resistant), which makes it incredibly difficult for traditional serums to reach the deeper layers where they’re needed most.

 Conformational Change™ Technology. Better Science For Deep Absorption

We use a proprietary platform called Conformational Change Technology™ that reorganizes active ingredients—like Deoxycholic Acid—into highly efficient, nano-sized molecular clusters.

This breakthrough happens without chemical modification. By guiding molecules to self-associate based on their hydrophilic (water-loving) and hydrophobic (water-resistant) regions, we create a system that effortlessly permeates the skin barrier.

The result? Superior absorption, faster results, and smarter skincare.

  • We don't just claim results. We measure them.

    Clinically Proven.

    Peer-Reviewed.

    Published.

  • Our formulas have been tested in independent clinical trials and published in peer-reviewed dermatology journals. Here's what happened when we put Conformational Change Technology™ to the test.

The Studies

  • CONFORMA REDUCE™

    Published in: Skin Research and Technology (2023)
    Participants: 42 women | Duration: 8 weeks

    Results:

    • 12.5% reduction in double chin surface area
    • 15.0% reduction in submental fat volume
    • Zero adverse effects reported
    • Visible results in 4-6 weeks

    The Bottom Line: Same active molecule as Kybella® injections ($1,640+ per session), delivered topically at a fraction of the cost with zero downtime.

  • CONFORMA HA™

    Published in: Journal of Cosmetic Dermatology (2022)
    Participants: 22 women, ages 29-59 | Duration: 4 weeks

    Results vs. Regular HA:

    • +8.1% improvement in skin elasticity
    • 22.1% greater reduction in water loss (stronger barrier)
    • 4.3% better improvement in facial lifting
    • 118-158% increase in collagen synthesis (regular HA: 0%)

    The Bottom Line: Not just surface hydration. This penetrates deeper, works harder, and actually stimulates your skin to produce more collagen.

How We Measured

Our studies weren't based on subjective opinions or self-reporting. We used clinical-grade equipment:
Vectra XT® 3D Imaging (measures volume changes)

DSLR Pixel Analysis (measures surface area)

Cutometer® (measures skin elasticity)

PRIMOS® (measures wrinkle depth)

Skin Scanner DUB USB (measures dermal density)

Laboratory ELISA Testing (measures collagen production)

Both studies were conducted at PNK Skin Research Center in Seoul, received IRB approval, and followed Helsinki Declaration ethical standards.

Most skincare brands talk about results.

We prove them.

Our technology isn't hiding behind "proprietary blends" or vague claims. It's published in international dermatology journals, tested by independent research centers, and measured using gold-standard equipment.

The Science FAQs

Where can I read the full studies?

Both peer-reviewed publications are available on our website. We believe in complete transparency.

Were these double-blind studies?

Yes. The Conforma HA™ study was randomized and double-blind. Participants used Conforma HA™ on one side of their face and regular HA on the other. Neither participant nor evaluator knew which side received which product.

How quickly will I see results?

For Conforma HA™: visible improvements within 2 weeks, measurable results by week 4. For Conforma Reduce™: noticeable changes around weeks 4-6, maximum results at 8 weeks with consistent use.

Are there side effects?

In our clinical trials with 64 participants over 4-8 weeks, zero adverse effects were reported. Both products use naturally occurring molecules (deoxycholic acid is produced by your liver; hyaluronic acid is already in your skin).

What happens if I stop using the products?

For Conforma Reduce™, eliminated fat cells don't return (permanent effect). For Conforma HA™, benefits gradually diminish if you stop, similar to any skincare product. Your skin won't worsen below your starting point.

What is Conformational Change Technology™?

It's a physical (not chemical) process that reorganizes molecules into nano-scale clusters (2-5nm) without using any additives or chemical modifications. Instead of forcing large molecules through the skin barrier, we physically restructure them into tiny clusters that penetrate easily, then reassemble once inside.

 How is "10X greater bioavailability" measured?

We measured this using synthetic membrane diffusion tests. After 72 hours, Conforma formulations showed approximately 10 times greater penetration through the membrane compared to standard formulations of the same molecule. This means significantly more of the active ingredient actually reaches its target in your skin.

It’s unlike anything else Revolutionary Results

  • 10x More Bioavailable

    Our conformational science is clinically proven to make active ingredients up to 10 times more bioavailable. This means more of the product is effectively absorbed and utilized by your skin, leading to superior, more noticeable results.

  • No Extra Chemicals

    Our technology uses physical molecular association—not chemical modification. This means we deliver active ingredients in their purest form, without unnecessary additives, ensuring maximum efficacy and integrity.

  • Amplifies Your Skincare

    Our Conformational Change Technology™ platform combines with and helps carry the active ingredients from your other favorite skincare products deeper into the skin for amplified results from your complete regimen.

real, visible results you'll love What This Means For Your Skin

Topical Fat-Reduction Comforma REDUCE

Redefine your jawline without needles. Our system allows DCA to effectively target stubborn fat deposits, visibly tightening your profile.

Hydrating Serum Comforma HA

Experience profound hydration as our technology delivers Hyaluronic Acid deep into the skin, plumping fine lines from within and restoring youthful elasticity.