Why Does Most Skincare Sit on the Surface? It's A Skin Barrier Problem

Did you know that up to 90% of skincare products never fully absorb?

The skin’s top job is protection. Its outer barrier is naturally hydrophobic (water-resistant), which makes it incredibly difficult for traditional serums to reach the deeper layers where they’re needed most.

 Conformational Change™ Technology. Better Science For Deep Absorption

We use a proprietary platform called Conformational Change Technology™ that reorganizes active ingredients—like Deoxycholic Acid—into highly efficient, nano-sized molecular clusters.

This breakthrough happens without chemical modification. By guiding molecules to self-associate based on their hydrophilic (water-loving) and hydrophobic (water-resistant) regions, we create a system that effortlessly permeates the skin barrier.

The result? Superior absorption, faster results, and smarter skincare.

It’s unlike anything else Revolutionary Results

  • 10x More Bioavailable

    Our conformational science is clinically proven to make active ingredients up to 10 times more bioavailable. This means more of the product is effectively absorbed and utilized by your skin, leading to superior, more noticeable results.

  • No Extra Chemicals

    Our technology uses physical molecular association—not chemical modification. This means we deliver active ingredients in their purest form, without unnecessary additives, ensuring maximum efficacy and integrity.

  • Amplifies Your Skincare

    Our Conformational Change Technology™ platform combines with and helps carry the active ingredients from your other favorite skincare products deeper into the skin for amplified results from your complete regimen.

real, visible results you'll love What This Means For Your Skin

Topical Fat-Reduction Comforma REDUCE

Redefine your jawline without needles. Our system allows DCA to effectively target stubborn fat deposits, visibly tightening your profile.

Hydrating Serum Comforma HA

xperience profound hydration as our technology delivers Hyaluronic Acid deep into the skin, plumping fine lines from within and restoring youthful elasticity.