Topical DCA serum
Inside The Formula.
Proprietary technology that delivers up to 10× deeper absorption.
Clinically Proven
Peer-Reviewed
Up to 90% of skincare actives never fully penetrate the skin barrier.
The skin’s top job is protection. Its outer barrier is naturally hydrophobic (water-resistant), which makes it incredibly difficult for traditional serums to reach the deeper layers where they’re needed most.
Conformational Change Technology
The Science Behind Deeper Absorption
We use a proprietary platform called Conformational Change Technology that reorganizes active ingredients — like Deoxycholic Acid — into highly efficient, nano-sized molecular clusters.
The process is physical — no chemical modification, no additives. By guiding molecules to self-associate based on their hydrophilic (water-loving) and hydrophobic (water-resistant) regions, we create a system that effortlessly permeates the skin barrier.
The result? Deeper absorption. Faster results. The science you can measure.
Traditional Topical
0–1mm
Conformational Change
Subcutaneous
Conformational Change Technology restructures active molecules so they absorb up to 10× more effectively than traditional formulations. Push-pull delivery carries Vitamin C and retinol deeper into the skin than they could travel alone.
Clinical Timeline for Conforma Reduce
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Day 1
Molecules restructure at the nano scale for deep absorption.
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Day 30
Visible jawline definition emerges with daily use.
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Day 60
Full results: 12.5% reduction in chin surface area.
Two Technologies
Two proprietary mechanisms, told end to end.
Developed in South Korea. Licensed exclusively for the U.S. market. Both technologies patent pending.
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Patent Pending
Conformational Change™ Technology.
- Cluster size
- 2–5 nm
- Bioavailability
- 10x
A proprietary process that physically restructures active molecules into nano-scale clusters between 2 and 5 nanometers — small enough to pass through the skin barrier and reach the subcutaneous layer where treatment is possible. No chemical modification. No additives. The same active, reorganized to do its work.
The technology behind Conforma Reduce.
-
Patent Pending
Push-Pull Delivery
Subcutaneous
- Collagen synthesis
- +118–158%
- Barrier strength
- +22.1%
A delivery system that turns hyaluronic acid into a molecular carrier. Smaller actives — Vitamin C, retinol, peptides — bind to the HA molecule and travel with it through the skin barrier to deeper layers than they could reach alone. The result: every active in your routine works harder.
The technology behind Conforma HA.
The evidence
Clinically Proven.
Peer-Reviewed. Published.
Two independent clinical studies, conducted at the PNK Skin Research Center in Seoul. Two peer-reviewed publications in international dermatology journals. Gold-standard measurement equipment, IRB approval, Helsinki Declaration compliance. Here’s what the studies measured.
The Studies
User and Clinical Trials
Conforma Reduce
- Published in:
- Skin Research and Technology (2023)
- Participants:
- 42 women
- Duration:
- 8 weeks
12.5% reduction in double chin surface area
15.0% reduction in submental fat volume
Zero adverse effects reported
Visible results in 4–6 weeks
Conforma HA™
- Published in:
- Journal of Cosmetic Dermatology (2022)
- Participants:
- 22 women, ages 29–59
- Duration:
- 4 weeks
+8.1% improvement in skin elasticity
22.1% greater reduction in water loss (stronger barrier)
4.3% better improvement in facial lifting
118–158% increase in collagen synthesis (regular HA: 0%)
How We Measured
Our studies weren’t based on subjective opinions or self-reporting. We used clinical-grade equipment:
Vectra XT® 3D Imaging
(measures volume changes)
DSLR Pixel Analysis
(measures surface area)
Cutometer®
(measures skin elasticity)
PRIMOS®
(measures wrinkle depth)
Skin Scanner DUB USB
(measures dermal density)
Laboratory ELISA Testing
(measures collagen production)
Both studies were conducted at PNK Skin Research Center in Seoul, received IRB approval, and followed Helsinki Declaration ethical standards.
FAQs
Where can I read the full studies?
Both peer-reviewed publications are available on our website. We believe in complete transparency.
Were these double-blind studies?
Yes. The Conforma HA™ study was randomized and double-blind. Participants used Conforma HA™ on one side of their face and regular HA on the other. Neither participant nor evaluator knew which side received which product.
How quickly will I see results?
For Conforma HA™: visible improvements within 2 weeks, measurable results by week 4. For Conforma Reduce™: noticeable changes around weeks 4-6, maximum results at 8 weeks with consistent use.
Are there side effects?
In our clinical trials with 64 participants over 4-8 weeks, zero adverse effects were reported. Both products use naturally occurring molecules (deoxycholic acid is produced by your liver; hyaluronic acid is already in your skin).
What happens if I stop using the products?
For Conforma Reduce™, eliminated fat cells don't return (permanent effect). For Conforma HA™, benefits gradually diminish if you stop, similar to any skincare product. Your skin won't worsen below your starting point.
What is Conformational Change Technology™?
It's a physical (not chemical) process that reorganizes molecules into nano-scale clusters (2-5nm) without using any additives or chemical modifications. Instead of forcing large molecules through the skin barrier, we physically restructure them into tiny clusters that penetrate easily, then reassemble once inside.
How is “10X greater bioavailability” measured?
We measured this using synthetic membrane diffusion tests. After 72 hours, Conforma formulations showed approximately 10 times greater penetration through the membrane compared to standard formulations of the same molecule. This means significantly more of the active ingredient actually reaches its target in your skin.
What Conformational Change makes possible.
Conforma Results
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10x More Bioavailable
Our conformational science is clinically proven to make active ingredients up to 10 times more bioavailable. This means more of the product is effectively absorbed and utilized by your skin, leading to superior, more noticeable results.
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No Extra Chemicals
Physical, not chemical. Conformational Change™ Technology restructures molecules through physical association — no chemical modification, no synthesized additives. The active reaches the skin in its original form, simply better delivered.
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Amplifies Your Skincare
Our Conformational Change Technology™ platform combines with and helps carry the active ingredients from your other favorite skincare products deeper into the skin for amplified results from your complete regimen.
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