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Behind the science

Dr. Edwin L. Parsley, D.O.

Founder & Scientific Lead, Conformational Aesthetics · Board-certified in Internal Medicine, Pulmonary Disease, Critical Care Medicine, and Sleep Medicine · Assistant Professor of Medicine (former), University of Texas Medical School - Houston · Owner and Medical Director, Aesthetica Med Spa of San Diego

Dr. Ed Parsley at Aesthetica Med Spa of San Diego, 2026
Dr. Ed Parsley at Aesthetica Med Spa of San Diego, 2026

Edwin Parsley is a physician and pharmaceutical drug developer with more than three decades of clinical practice, academic medicine, and pharmaceutical clinical trial experience.

Board-certified in four specialties, he trained in pulmonary and critical care medicine at the University of Texas Medical School - Houston, where he served as Assistant Professor of Medicine and Medical Director of the Medical Intensive Care Unit at Memorial Hermann Hospital.

For nearly two decades, Dr. Parsley has led drug development programs at pharmaceutical companies including Pfizer, where he served as Senior Director and Clinical Lead for Revatio in 2010. He has held Chief Medical Officer roles at seven pharmaceutical companies developing treatments for pulmonary arterial hypertension, sickle cell disease, and cystic fibrosis, and continues to serve as Medical Monitor for active clinical trials in pulmonary vascular disease.

In 2016, Dr. Parsley opened Aesthetica Med Spa of San Diego, where he practices aesthetic medicine and provides ongoing patient care. Conformational Aesthetics is the extension of that work — a skincare line developed under the same clinical trial standards Dr. Parsley applies to prescription drug development, addressing the gap between what patients could receive in a clinical setting and what they could take home.

Be the numbers

A record that speaks for itself.

37+

Years in Medicine

Practice began with residency at UT Houston in 1989.

4

Board Certifications

Internal Medicine · Pulmonary Disease · Critical Care Medicine · Sleep Medicine

10

Years Academic Faculty

Assistant Professor of Medicine at UT Medical School - Houston.

7

Pharmaceutical CMO Roles

Chief Medical Officer or Acting CMO across the industry.

7

Peer-Reviewed Publications

Including the New England Journal of Medicine.

200+

ICU Admissions Per Month

Under his medical direction at Memorial Hermann Hospital.

Origins

Pharmacy before medicine

Weatherford, Oklahoma · 1979–1988

Dr. Parsley grew up in Oklahoma. He graduated from Southwestern Oklahoma State University in 1984 with a Bachelor of Science in Pharmacy, Summa Cum Laude, earning honors including the Eli Lilly and Company Achievement Award and election as President of the Rho Chi Pharmacy Honor Society.

Rather than practicing pharmacy, he continued his training in medicine. He entered Oklahoma State University College of Osteopathic Medicine and graduated in 1988, second in a class of seventy-five, with a 3.88 GPA. He was named to the Dean's List every year and awarded the Scott Silver Memorial Microbiology Award.

The pharmacy training would prove foundational. It gave him a working understanding of drug design, chemistry, and pharmacokinetics that would later distinguish his work as a pharmaceutical clinical developer.

The critical care years

A decade in the ICU.

Houston, Texas · 1989–2006

After a transitional internship at Flint Osteopathic Hospital in Michigan, Dr. Parsley completed his internal medicine residency at the University of Texas Medical School at Houston from 1989 to 1992, then served as Chief Medical Resident. He completed his fellowship in Pulmonary and Critical Care Medicine at UT Houston from 1993 to 1996.

He joined the UT Houston faculty as Assistant Professor of Medicine in 1996 and spent the next decade leading intensive care medicine at Memorial Hermann Hospital, one of the largest teaching hospitals in Texas. As Medical Director of the Medical Intensive Care Unit from 2000 to 2005, he oversaw a service with more than 200 admissions per month.

During this period he also directed the hospital's Pulmonary Function Laboratory and Respiratory Care Services, taught pulmonary and critical care fellows, internal medicine residents, and medical students, and conducted research on pulmonary complications of scleroderma.

His clinical research contributed to the pivotal New England Journal of Medicine trial on cyclophosphamide for scleroderma lung disease, published in 2006. He was named Physician of the Year at Memorial Hermann Hospital in 2003.

Silent Care Clinic
From 1996 to 1999, Dr. Parsley also directed the Silent Care Clinic, a teaching facility of UT Houston and the only clinic in Texas dedicated to healthcare for Deaf adults.

Drug development

Building drugs for the world's rarest lungs.

Global · 2006–present

In 2006, Dr. Parsley left academic medicine to lead pharmaceutical drug development, joining Encysive Pharmaceuticals as Executive Director of Global Medical Affairs and Drug Safety.

In 2010, he joined Pfizer Global Research and Development in New York as Senior Director and Pulmonary Vascular Disease Area Medical Lead. He served as Clinical Lead for Revatio, Pfizer's sildenafil-based pulmonary arterial hypertension treatment, overseeing pediatric and adult studies, safety monitoring, and global regulatory strategy across the United States, European Union, Canada, Australia, and Japan.

Since Pfizer, Dr. Parsley has led pulmonary hypertension drug development programs for over a dozen pharmaceutical companies. He continues to serve as Medical Monitor Consultant for Pulmovant, Mycovia Pharmaceuticals, Gossamer Bio, and Liquidia Technologies.

2006

Encysive Pharmaceuticals

Executive Director, Global Medical Affairs

2010

Pfizer

Senior Director, Clinical Lead for Revatio

2011–2017

Aires Pharmaceuticals · Mast Therapeutics

Chief Medical Officer

2018–present

Liquidia · Gossamer · Pulmovant

Medical Monitor Consultant

Aesthetica Med Spa

Happy medicine

San Diego, California · 2016–present

In October 2016, Dr. Parsley opened Aesthetica Med Spa of San Diego on Camino del Rio South. The practice offers aesthetic treatments including injectable neurotoxins, hyaluronic acid and other fillers, radiofrequency microneedling, laser and light-based therapies, ultrasonic treatments, lipolysis with CoolSculpting and Emsculpt, and deoxycholic acid injections.

Dr. Parsley personally administers all injectable procedures and directly oversees every treatment provided.

Aesthetics is happy medicine. I get to help people feel better, not just survive.

His practice at Aesthetica has since informed the entire development trajectory of Conformational Aesthetics. Every treatment in the Conforma line reflects a clinical problem Dr. Parsley encountered in his own patients — most notably, patients who considered Kybella or in-office fat-reduction procedures but chose not to pursue them because of cost, downtime, or the injection experience itself.

Conformational Aesthetics

A question he
kept asking.

Founded in San Diego, developed in Seoul

Conformational Aesthetics was founded on a specific question Dr. Parsley kept asking his own patients: what if the treatment they were considering could be delivered without the appointment?

His pharmaceutical background made him uniquely equipped to answer that question. He knew what clinical evidence looked like. He knew what safety monitoring required. He knew where the boundary sat between marketing claims and defensible science.

Working with a research laboratory in South Korea, Dr. Parsley identified a proprietary delivery technology capable of restructuring active molecules at the nano scale — small enough to pass through the skin barrier and reach the tissue layers where the actives could actually work.

Every formula in the Conformational Aesthetics line is developed and reviewed under the same clinical trial standards Dr. Parsley applies to his ongoing pharmaceutical drug development work.

Published research.

2006

Cyclophosphamide versus placebo in scleroderma lung disease.

Tashkin DP, Parsley E, et al. New England Journal of Medicine. 354(25): 2655–66.

2007

Effect of 1-year treatment with cyclophosphamide on outcomes at 2 years in scleroderma lung disease.

Tashkin DP, Parsley E, et al. American Journal of Respiratory and Critical Care Medicine. 176: 1026–1034.

2007

Impact of oral cyclophosphamide on health-related quality of life in patients with active scleroderma lung disease.

Khanna D, Parsley E, et al. Arthritis & Rheumatism. 56(5): 1676–84.

2008

Risk-based fluconazole prophylaxis of Candida bloodstream infection in a medical intensive care unit.

Faiz S, Parsley E, et al. European Journal of Clinical Microbiology & Infectious Diseases.

2004

Alveolar macrophages from systemic sclerosis patients: evidence for IL-4-mediated phenotype changes.

Hamilton RF, Parsley E, Holian A.

Board Certifications & Honors

Conformational Aesthetics

1993

Internal Medicine

1996

Pulmonary Disease

1997

Critical Care Medicine

2005

Sleep Medicine

All certifications through the American Board of Internal Medicine or the American Board of Sleep Medicine. Fellow, American College of Chest Physicians.

Selected Honors

2003

Physician of the Year

Memorial Hermann Hospital

2000-2001

Dean's Teaching Excellence Award

University of Texas Medical School - Houston

1999

Alfred Soffer Research Award

American College of Chest Physicians

2004

Mavis Thomas Award

Memorial Hermann Hospital Infection Control

The Line He Built

Every formula
reviewed by Dr. Parsley.

Conformational Aesthetics applies the same clinical trial standards used in pharmaceutical drug development to skincare formulation and claim substantiation.